bpp: Computations Around Bayesian Predictive Power

Implements functions to update Bayesian Predictive Power Computations after not stopping a clinical trial at an interim analysis. Such an interim analysis can either be blinded or unblinded. Code is provided for Normally distributed endpoints with known variance, with a prominent example being the hazard ratio.

Version: 1.0.6
Depends: mvtnorm, R (≥ 3.5.0)
Suggests: knitr, rmarkdown
Published: 2025-02-22
DOI: 10.32614/CRAN.package.bpp
Author: Kaspar Rufibach [aut, cre], Paul Jordan [aut], Markus Abt [aut]
Maintainer: Kaspar Rufibach <kaspar.rufibach at gmail.com>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: no
Materials: NEWS
CRAN checks: bpp results

Documentation:

Reference manual: bpp.pdf
Vignettes: Sequentially updating the likelihood of success of a Phase 3 pivotal time-to-event trial based on interim analyses or external information (source, R code)

Downloads:

Package source: bpp_1.0.6.tar.gz
Windows binaries: r-devel: bpp_1.0.6.zip, r-release: bpp_1.0.6.zip, r-oldrel: bpp_1.0.6.zip
macOS binaries: r-devel (arm64): bpp_1.0.6.tgz, r-release (arm64): bpp_1.0.6.tgz, r-oldrel (arm64): bpp_1.0.6.tgz, r-devel (x86_64): bpp_1.0.6.tgz, r-release (x86_64): bpp_1.0.6.tgz, r-oldrel (x86_64): bpp_1.0.6.tgz
Old sources: bpp archive

Linking:

Please use the canonical form https://CRAN.R-project.org/package=bpp to link to this page.